Progressive Multifocal Leukoencephalopathy in a Child as First Manifestation of Congenital Human Immunodeficiency Virus Infection

Full Article

DD Rasalkar, WCW Chu, BK Paunipagar, ELW Fung

Hong Kong J Radiol 2010;12:131-5

This report is of a 13-year-old girl who presented with progressive multifocal leukoencephalopathy as the first manifestation of congenital human immunodeficiency virus infection. Progressive multifocal leukoencephalopathy is a severe demyelinating disease of the central nervous system caused by JC papovavirus infection. The prognosis is poor, with a fatal outcome within 1 year for 90% of patients.

 

中文摘要

首發症狀為進行性多灶性腦白質病的先天性人免疫缺陷病毒(HIV)感染兒童

DD Rasalkar、朱昭穎、BK Paunipagar、ELW Fung

本文報導一例感染先天性人免疫缺陷病毒(HIV),首發症狀為進行性多灶性腦白質病的13歲女童情 況。進行性多灶性腦白質病是由一種JC病毒(乳頭狀瘤多瘤空泡形病毒)感染引起的中樞神經系統嚴 重脫髓鞘病變。該病預後很差,1年內死亡率達90%。