A Pictorial Review of Immunoglobulin G4-related Sclerosing Disease

Full Article

SM Yu, TKL Loke, JTH Yeung, WH Luk, LKM Wong

Hong Kong J Radiol 2014;17:208-17

DOI: 10.12809/hkjr1413200

Immunoglobulin (Ig) G4-related sclerosing disease is a relatively new disease entity. Any organ system can be affected. Therefore, there is a wide range of possible clinical manifestations. Diagnosis is often difficult and relies on a combination of radiological features, laboratory data, and histology findings. IgG4-related sclerosing diseases are frequently found to be associated with autoimmune pancreatitis. There are several established diagnostic criteria that are used to diagnose autoimmune pancreatitis. In our centre, we use the Asian Diagnostic Criteria for Autoimmune Pancreatitis in 2008. A total of 10 cases with proven IgG4-related systemic disease from 2008 to 2012 were reviewed. This pictorial essay aimed to share our imaging findings among patients with proven IgG4-related sclerosing disease.