Two Cases of Gastrointestinal Stromal Tumour Presenting Uncommonly as Intraperitoneal Rupture in Patients Prescribed Warfarin

Full Article

RCH Nung, SSM Wong, RKL Lee, ABW Chan, YYP Lee

Hong Kong J Radiol 2016;19:132-6

DOI: 10.12809/hkjr1615376

Gastrointestinal stromal tumour (GIST) is the most common mesenchymal neoplasm of the gastrointestinal tract. Common presentations of GIST include early satiety, indigestion, bloating, vague abdominal pain, and gastrointestinal bleeding. Intraperitoneal rupture is an uncommon presentation of GIST. We have encountered two patients prescribed warfarin, who presented with intraperitoneal haemorrhage as their initial presentation of gastric GIST. Computed tomography (CT) revealed a submucosal gastric mass with intralesional and intraperitoneal haemorrhage. The diagnosis of ruptured GIST was made based on CT findings. These two cases are, to the best of our knowledge, the first two cases with rupture and intraperitoneal haemorrhage as the initial presentation of gastric GIST while on warfarin.

 

中文摘要

 

服用華法林患者出現罕見的胃腸道間質瘤腹腔內破裂後被確診為胃腸道間質瘤:兩例報告

農智行、王先民、李嘉樂、陳碧雲、李艷萍

 

胃腸道間質瘤(GIST)是胃腸道最常見的間質腫瘤。GIST的常見症狀包括易飽、消化不良、腹脹、腹部疼痛和消化道出血。腹腔內破裂是GIST的一種罕見的症狀。本文報告兩名服食華法林的GIST病人出現腹腔內破裂。CT顯示粘膜下胃腫塊及病變內和腹腔出血。後因CT檢查結果而被確診為GIST。據我們所知,這兩個為首個類似的病例。