Diagnosing Gout with Dual-energy Computed Tomography: Principles, Diagnostic Performance, and Clinical Application

Full Article

JPK Tsang, MK Yuen

Hong Kong J Radiol 2017;20:98-102

DOI: 10.12809/hkjr1716838

Gout is an inflammatory response to deposition of monosodium urate (MSU) crystals in soft tissues and joints, and is the most common form of inflammatory arthritis in adults. Dual-energy computed tomography (CT) is a non-invasive tool for diagnosis, volume quantification of MSU crystals, and monitoring of treatment response. Dual-energy CT is included in the 2015 American College of Rheumatology / European League Against Rheumatism gout classification criteria. Although dual-energy CT has lower sensitivity when restricted to individual crystal-proven gouty joints in non-tophaceous disease, its diagnostic performance is good to excellent for tophaceous gout.


Authors’ affiliation:
JPK Tsang, MK Yuen: Department of Radiology, Tuen Mun Hospital, Tuen Mun, Hong Kong