The Impact of Thyroid Sonoelastography in Preventing Irrational Needle Biopsies in Evaluation of Benign Thyroid Nodules

Full Article

S Wahab, I Ahmad

Hong Kong J Radiol 2018;21:107-13

DOI: 10.12809/hkjr1816829

Objective: Ultrasound elastography involves combining the diagnostic advantages of high-frequency ultrasound examination and the accuracy of thyroid cancer diagnosis based on the nodule’s stiffness. This study aimed to evaluate the elastographic appearances of different types of thyroid gland nodules and to explore the real diagnostic value and clinical utility of thyroid ultrasound elastography with histopathological analysis as a reference standard.
Methods: A total of 72 sonographically visible thyroid nodules were included and their elastographic appearance being classified into six classes. Results of strain or quasistatic elastography were compared with pathological results on fine-needle aspiration cytology/biopsy and statistical analysis performed with calculation of sensitivity, specificity, as well as positive and negative predictive values.
Results: A total of 42 nodules were diagnosed as malignant and 30 as benign on elastography. On histopathological analysis, 37 nodules were found malignant including 31 cases of papillary carcinoma and six of follicular carcinoma. The sensitivity, specificity, positive and negative predictive values of thyroid ultrasound elastography with histopathological diagnosis as reference standard were 97.29%, 82.85%, 85.71% and 96.67%, respectively.
Conclusion: Thyroid elastography can greatly reduce the rate of thyroid biopsies especially in benign-appearing lesion.


Author affiliation(s):
S Wahab, I Ahmad: Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India





S Wahab, I Ahmad