Vol. 15 No. 4 Supplement, 2012

Table of Contents


Update on the Management of Advanced Ovarian Cancer: the Role of Anti-angiogenic Agents

Full Article

SB Kaye

Hong Kong J Radiol 2012;15(Suppl):S5-12

Ovarian cancer is often diagnosed in its later stages, leading to poor prognosis and high mortality rates. Chemotherapy with paclitaxel plus a platinum-based drug is the standard treatment for advanced ovarian carcinoma.

Recent Advances in the Treatment of Hepatocellular Carcinoma

Full Article

RTP Poon

Hong Kong J Radiol 2012;15(Suppl):S13-22

Multiple factors may influence the selection of treatments for patients with hepatocellular carcinoma. Surgical resection continues to be the mainstay of treatment for patients with well-preserved liver function.

Molecular Pathogenesis of Hepatocellular Carcinoma

Full Article


Hong Kong J Radiol 2012;15(Suppl):S23-8

Liver cancer, which consists predominantly of hepatocellular carcinoma, is one of the most frequently occurring cancers and the third most common cause of cancer death worldwide.

A Non-invasive Weapon: Image-guided Radiotherapy for Hepatocellular Carcinoma

Full Article

ALY Law, WT Ng, SYJ Ka, RMW Yeung

Hong Kong J Radiol 2012;15(Suppl):S29-32

The high prevalence of chronic hepatitis B virus infection in Hong Kong makes hepatocellular carcinoma one of the area’s most important solid tumours. Late presentation and underlying cirrhosis mean that many hepatocellular carcinomas are inoperable at first presentation.

Evolution of Neoadjuvant Chemoirradiation in Rectal Cancer

Full Article

KO Lam

Hong Kong J Radiol 2012;15(Suppl):S33-9

The treatment of rectal cancer is evolving and it nicely demonstrates the beauty of multimodality treatment. Unlike total mesorectal excision in surgery, which has probably marked the climax in the advancement of surgical treatment of rectal cancer,

Predictive Molecular Biomarkers in Targeted Therapy of Gastric Carcinoma and Metastatic Colorectal Carcinoma

Full Article


Hong Kong J Radiol 2012;15(Suppl):S40-5

With the recent advancement of molecular targeting therapy, we are witnessing a paradigm shift in the role of pathology laboratories in the management of solid tumours.

New Directions in Anti-angiogenesis Therapy in Metastatic Colorectal Cancer

Full Article

HH Loong, BBY Ma

Hong Kong J Radiol 2012;15(Suppl):S46-50

Mortality from metastatic colorectal cancer has declined over the past decade, partly due to improvement in survival secondary to incorporation of targeted biologics in the treatment paradigm.

HER2-positive Metastatic Breast Cancer: New Agents on the Horizon

Full Article

W Yeo

Hong Kong J Radiol 2012;15(Suppl):S51-6

The human epidermal growth factor receptor HER2/neu gene is amplified and overexpressed in 25 to 30% of breast cancers. In women with HER2-positive advanced or metastatic breast cancer,

Revisiting the Role of Anti-angiogenesis Therapy in Metastatic Breast Cancer

Full Article

CH Kwok

Hong Kong J Radiol 2012;15(Suppl):S57-63

Angiogenesis is essential for tumour growth and metastasis, and constitutes an important process in the control of cancer progression. The use of anti-angiogenic agents, particularly those targeting vascular endothelial growth factor,

Treatment of Advanced Non–small-cell Lung Cancer: a Fast Changing Paradigm

Full Article

P Teo

Hong Kong J Radiol 2012;15(Suppl):S64-71

Palliative chemotherapy and / or radiotherapy continue to represent the standard of care for patients with inoperable, advanced-stage non–small-cell lung cancer.

Update on Biosimilars — Complexity of Biologics and Clinical Concerns: Importance of Proper Evaluation

Full Article


Hong Kong J Radiol 2012;15(Suppl):S72-4

Biopharmaceuticals or biologics were first introduced at the beginning of the 1980s and are now well established in the treatment of a wide variety of diseases. Biosimilars are biopharmaceuticals that are similar, but not identical,


Management of Castleman’s Disease: Recent Advances and Case Sharing

Full Article

RSM Wong

Hong Kong J Radiol 2012;15(Suppl):S75-80

Castleman’s disease is an uncommon lymphoproliferative disorder characterised by hyperplasia of lymphoid tissue. There are three histopathological types of Castleman’s disease: hyaline vascular variant, plasma cell variant, and mixed cellularity.

Case Sharing in T-cell Lymphomas and Review of Angioimmunoblastic T-cell Lymphoma

Full Article

YK Lam

Hong Kong J Radiol 2012;15(Suppl):S81-4

Mature T-cell and natural killer–cell neoplasms can be classified into four categories based on site: cutaneous, extranodal, nodal, and leukaemic. Subtypes within these categories may be aggressive or indolent,

Relapsed Hodgkin’s Lymphoma after Autologous Bone Marrow Transplant

Full Article


Hong Kong J Radiol 2012;15(Suppl):S85-7

This report describes a 28-year-old woman with stage IV Hodgkin’s lymphoma with nodular sclerosis and bone marrow involvement. The patient received four cycles of adriamycin, bleomycin, vinblastine, and dacarbazine combination chemotherapy

Use of Bevacizumab in Combination with Chemotherapy in Ovarian Cancer in a Community Practice Setting

Full Article

K Loh

Hong Kong J Radiol 2012;15(Suppl):S88-92

Although ovarian cancers tend to be fairly chemo-responsive initially, the difficulty facing clinicians is maintaining or prolonging the duration of disease control.

A Multidisciplinary Approach to the Management of Unresectable Hepatocellular Carcinoma

Full Article

CKK Choi

Hong Kong J Radiol 2012;15(Suppl):S93-5

With the advances that have been made in the field of radiation technology over the past decade, radiotherapy has become a feasible and promising treatment modality for hepatocellular carcinoma.