Inoperable Adenoid Cystic Carcinoma of Trachea: Complete Remission after Multi-modality Treatment
WL Chan, VHF Lee, SWK Siu, TW Leung
Hong Kong J Radiol 2014;17:203-7
DOI: 10.12809/hkjr1413202
Adenoid cystic carcinoma is a malignant tumour commonly originating from the salivary glands, but can rarely arise from the upper airway and be life threatening when the central airway is compromised. While surgical resection is considered the definitive treatment, adenoid cystic carcinoma of the airway is frequently unresectable for a variety of reasons including tumour size, location, local extension, or patient comorbidities. There is no consensus on the best treatment for locally advanced inoperable adenoid cystic carcinoma of trachea. This case report describes a 32-year-old woman with inoperable adenoid cystic carcinoma of trachea successfully managed in our institution using a multimodality approach: endoscopic stenting followed by 3-dimensional conformal radical radiotherapy. Previous literature on the management of this rare disease is also reviewed.
中文摘要
不能以手術切除的氣管腺樣囊性癌：多模式治療後完全緩解
陳穎樂、李浩勳、蕭偉君、梁道偉
腺樣囊性癌是一種惡性腫瘤，通常源於唾液腺；但也可罕見地源於上呼吸道，當累及中央氣道時，患者便會有生命危險。縱然手術切除被認為是規定治療，可惜氣管上的腺樣囊性癌大多不能切除。原因有多種，包括腫瘤大小、位置、局部擴散或病人的合併症。關於不能以手術切除的局部進展性氣管腺樣囊性癌的最佳治療方案，尚未達成共識。本文報告本中心成功治療的一名患有氣管腺樣囊性癌但不能以手術切除的32歲女性；方案為多種方式聯合治療，即以內鏡下支架置入後再以三維適形根治性放療。本文同時回顧以往有關這種罕見疾病治療方法的文獻。